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Urinary tract infection

Symptoms, when it is more serious, how to ease it, treatment and prostatitis.

Dr. Petronio Melo, urologistCRM-SP 157.598 · RQE 70.275
Reviewed by Dr. Petronio Melo on November 8, 2026
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Drawing of the kidneys, ureters and bladder, with bacteria moving up the urethra
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Quick answer

A urinary tract infection is an infection of the urinary tract, usually caused by bacteria. The most common form is cystitis, in the bladder, with burning when urinating, frequency and urgency.1,2 With fever, chills or back pain, the infection may have reached the kidney, and evaluation should happen the same day.3 The antibiotic is chosen according to where the infection is and each person's situation.1

What it is

Bacteria usually enter through the urethra and multiply in the bladder.2 If the infection is not treated, it can travel up to the kidneys.2 About half of women will have a bladder infection during their lives, and about a quarter of them will have repeated infections.2

Schematic animation: the infection starts low down and, without treatment, can travel up to the kidney.

Symptoms

In the bladder, the most common symptoms are:3

  • burning when urinating
  • a frequent and strong need to urinate, even with little urine
  • discomfort in the lower abdomen
  • urine that is cloudy, bloody or strong-smelling

When the infection reaches the kidney, fever, chills, nausea or vomiting and pain in the back, side or groin appear.3

Comparison between cystitis and kidney infection. In the bladder: burning, urgency and frequent trips to the toilet, without fever. In the kidney: fever, chills, back pain, nausea or vomiting.
Diagram: fever is the main sign that the infection may have left the bladder.

Who is at higher risk

  • sexual activity and menopause2
  • a diaphragm or spermicide as contraception2
  • a previous urinary tract infection2
  • difficulty emptying the bladder and use of a catheter2
  • a blockage, such as a stone or an enlarged prostate2
  • abnormalities of the urinary tract2
  • diabetes and immune problems2

How to ease the symptoms

Painkillers, rest and enough fluid to keep the urine clear help with the discomfort.4 Coffee and alcohol can be avoided for those days.4

These measures ease symptoms but do not replace evaluation. Avoid using leftover antibiotics at home: the choice depends on where the infection is, and some widely used antibiotics are not recommended for cystitis.1

How it is diagnosed

In women with burning, urgency and frequent trips to the toilet, without vaginal discharge, the history alone makes cystitis very likely.1 A urine test helps with the evaluation.1

The European guideline recommends a urine culture when an infection beyond the bladder is suspected, with atypical symptoms, with symptoms that do not improve or come back within 4 weeks of treatment, with a risk of resistant bacteria and in pregnancy.1 In my practice, I always order a urine culture, except for a first episode of uncomplicated cystitis in women.

When kidney infection is suspected, imaging is ordered selectively. CT comes in when fever continues after 48 to 72 hours of treatment or when a complication is suspected.1

How it is treated

Cystitis. The European guideline recommends fosfomycin, nitrofurantoin and other short-course antibiotics, and asks that aminopenicillins and fluoroquinolones not be used for cystitis.1 The antibiotic depends on each institution's protocol, and for uncomplicated cystitis I usually start with fosfomycin or nitrofurantoin. See more in cystitis.

Kidney infection. The antibiotics for cystitis do not work: nitrofurantoin, oral fosfomycin and pivmecillinam should not be used.1 Treatment can be at home or in hospital, depending on severity.1

In men. Infections limited to the bladder are rare, and nitrofurantoin should only be used if the prostate is not involved.1

Urinary tract infections that come back

An infection is called recurrent when there are at least 3 episodes in a year or 2 in 6 months.1 In these cases, I try to understand what lies behind it, and prevention follows an order: first avoiding risk factors, then non-antibiotic measures and, only then, preventive antibiotics.1 The details are in cystitis.

Abnormal test, no symptoms

Bacteria in the urine without any symptoms is called asymptomatic bacteriuria. The European guideline recommends not screening for it or treating it in most people, including women after menopause, older people, people with controlled diabetes and people with recurrent urinary tract infections.1 In that last group, treating it is harmful.1

The exceptions are pregnancy and urological procedures that breach the mucosa.1

Prostatitis

Prostatitis is inflammation of the prostate. The bacterial form can be acute or chronic.

Comparison between acute and chronic bacterial prostatitis. Acute: starts suddenly, with fever, malaise, pain and difficulty urinating, and antibiotics for 2 to 4 weeks. Chronic: symptoms for 3 months or more, with pain in the perineum, scrotum, penis or inner thigh, and antibiotics for 4 to 6 weeks.
Diagram: the two forms of bacterial prostatitis.

In the acute form, a urine culture is the most important test, and prostate massage should not be done.1 After improvement, treatment continues by mouth, to complete 2 to 4 weeks.1

In the chronic form, symptoms last at least 3 months, and staged urine tests help identify the bacterium.1 The antibiotic is used for 4 to 6 weeks after diagnosis.1

Where to start

When to see a urologist

  • If you have symptoms of a urinary tract infection and are a man, pregnant, have diabetes, use a catheter or are over 654
  • If symptoms get worse quickly or do not improve in 48 hours4
  • If the infection comes back 2 times in 6 months or 3 times in a year1,4
  • If there is blood in the urine4

Frequently asked questions

What is a urinary tract infection?

It is an infection of the urinary tract, usually caused by bacteria. The most common form is cystitis, which is in the bladder.1,2

What are the symptoms of a urinary tract infection?

Burning when urinating, a frequent and strong need to urinate even with little urine, discomfort in the lower abdomen and urine that is cloudy, bloody or strong-smelling.3

How do I know if the infection has reached the kidney?

Fever, chills, nausea or vomiting and pain in the back, side or groin suggest a kidney infection.3 These signs call for evaluation the same day.

How can I ease a urinary tract infection right away?

Painkillers, rest and fluids help with the symptoms.4 They do not treat the infection. If the cause is bacterial, treatment is with antibiotics, and the right step is to be evaluated before choosing which one.1

Does a urinary tract infection cause discharge?

The European guideline considers the absence of vaginal discharge part of the typical picture of cystitis.1 Discharge, in women or men, points to other causes, such as [urethritis](/en/sexually-transmitted-infections/urethritis/), and needs evaluation.

Does an abnormal urine test without symptoms need antibiotics?

For most people, no. The European guideline only recommends treating bacteria in the urine without symptoms during pregnancy and before urological procedures that breach the mucosa.1

Do men get urinary tract infections?

Yes, but men under 50 rarely have a bladder infection.2 When it happens, the prostate and bladder emptying are part of the evaluation.1,2

Does PSA rise with prostatitis?

It can. PSA is raised in about 60% of men with acute bacterial prostatitis and in 20% of those with the chronic form.1

References

  1. European Association of Urology. EAU Guidelines on Urological Infections. EAU
  2. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Definition & Facts of Bladder Infection in Adults. NIH
  3. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Symptoms & Causes of Bladder Infection in Adults. NIH
  4. National Health Service (NHS). Urinary tract infections (UTIs). NHS

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